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Nutritional Health (related to Food Induced Immune Response (FIIR))

β-Mannans: the problem component in soybean meal.
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Nutritional Health (related to Food Induced Immune Response (FIIR))

β-Mannans: the problem component in soybean meal.

β-Mannans (beta-galactomannans) are antinutritive fibers found in common feed ingredients, including soybean meal and other leguminous feeds.1-4 β-Mannans have a molecular pattern similar to some pathogens, which triggers a Feed-Induced Immune Response (FIIR) in poultry intestines.5-9 This unnecessary response consumes energy10,11 and other valuable nutrients. The overall effect is to reduce the efficiency of poultry diets containing β-Mannans.

In order to reduce the effect of β-mannans in poultry diets, a health enzyme can be incorporated into poultry feed. This enzyme breaks down the β-mannans, thus preventing FIIR from occurring. As a result, important energy in poultry diets is not lost and can be used to benefit poultry growth and development.

1 Hsiao, H., Anderson, D. and Dale, N. 2006. "Levels of β-mannan in Soybean Meal." Poultry Sci. 85: 1430-1432.

2Slominski, B. and Campbell, L. 1990. "Non-starch Polysaccharides of Canola Meal: Quantification, Digestibility in Poultry and Potential Benefit of Dietary Enzyme Supplementation." J. Sci. Food Agri. 53: 175-184.

3Whistler, R. and Saarnio, J. 1957. "Galactomannan from Soy Bean Hulls." J. Am. Chem. Soc. 79: 6055-6057.

4Dierick, N. 1989. "Biotechnology aids to improve feed and feed digestion: Enzymes and fermentation." Archives of Animal Nutrition (Berlin). 39:3: 241-246.

5Song, W., Wang, G., Chen, L. et al. 1995. "A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, Xa21." Science. 270: 1806-1806.

6Beutler, B., Jiang, Z., Georgel, P. et al. 2006. "Genetic Analysis of Host Resistance: Toll-Like Receptor Signaling and Immunity at Large." Annu. Rev. Immunol. 24: 353-389.

7Ausubel, F. 2005. "Are innate immune signaling pathways in plants and animals conserved?" Nature Immunol. 6(10): 973-979.

8Didierlaurent, A., Simonet, M. and Sirard, J-C. 2005. "Innate and acquired plasticity of the intestinal immune system." Cellular and Molecular Life Sciences. 62: 1285-1287.

9Stahl, P. and Ezekowitz, R. 1998. "The mannose receptor is a pattern recognition receptor involved in host defense." Curr. Opin. Immunol. 10(1): 50-55.

10Spurlock, M. 1997. "Regulation of metabolism and growth during immune challenge: an overview of cytokine function." J. Anim. Sci. 75: 1773-1783.

11Klasing, K. 2007. "Nutrition and the immune system." Br. Poult. Sci. 48(5): 525-537.